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11 April 2003

PPL spins off cloning business

Reproduced from The Courier, 11 April 2003

(Filed 11 April 2003)
www.land-care.org.uk

THE COMPANY that created Dolly the sheep yesterday completed its withdrawal from the cloning techniques for which it became famous as it reshapes to concentrate on more profitable markets.

PPL Therapeutics, which is based in Edinburgh has agreed to spin-off its US-based regenerative medicine business – which undertakes research based on stem cells.

The unit will be sold to Regenecor Holdings, a new company formed by a join venture which includes the University of Pittsburgh’s medical centre.

In a statement, PPL said, "The board of PPL does not believe it is possible for PPL to be successful in developing both its core protein business and the regenerative medicine business within the financial and management resources currently available to it."

PPL revealed its intention to sell its regenerative medicine cloning business last year after sinking millions of pounds into the project.

Chief executive Geoff Cook wants to concentrate on developing new protein treatments for lung disease and cystic fibrosis.

Yesterday he said, “By spinning out this area of our business we have an important milestone in the strategy put in place by PPL’s management team to focus on the business on the development of protein based therapeutics.”

PPL is now focused on developing and producing human proteins for therapeutic applications.

Copies of human DNA are introduced into the genetic material of another species - usually sheep - and the product is collected through an animal's milk. The company is also working to overcome the causes of rejection for organs transplanted in humans.

PPL retains the rights to its cloning technology but a spokesman said it had no current plans to undertake any work in the area.

PPL shares were up 0.12p at 6.37p.